High-frequency homologous recombination in vaccinia virus DNA.
A recombinant vaccinia virus genome was constructed in which the viral thymidine kinase (tk) gene was placed between direct repeats of a 1.5-kilobase-pair DNA sequence of heterologous origin. When forced to replicate in tk- cells in the presence of methotrexate (i.e., under tk+-selective conditions)...
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| Udgivet i: | J Virol |
|---|---|
| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1987
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254181/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3573150/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.6.1788-1795.1987 |
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