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Identification of Novel Temperature-sensitive Lethal Alleles in Essential β-Tubulin and Nonessential α2-Tubulin Genes as Fission Yeast Polarity Mutants

We have screened for temperature-sensitive (ts) fission yeast mutants with altered polarity (alp1–15). Genetic analysis indicates that alp2 is allelic to atb2 (one of two α-tubulin genes) and alp12 to nda3 (the single β-tubulin gene). atb2(+) is nonessential, and the ts atb2 mutations we have isolat...

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Bibliographic Details
Main Authors: Radcliffe, Pippa, Hirata, Dai, Childs, Dylan, Vardy, Leah, Toda, Takashi
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 1998
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC25415/
https://ncbi.nlm.nih.gov/pubmed/9658169
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