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A Fourth Component of the Fission Yeast γ-Tubulin Complex, Alp16, Is Required for Cytoplasmic Microtubule Integrity and Becomes Indispensable When γ-Tubulin Function Is Compromised

γ-Tubulin functions as a multiprotein complex, called the γ-tubulin complex (γ-TuC), and composes the microtubule organizing center (MTOC). Fission yeast Alp4 and Alp6 are homologues of two conserved γ-TuC proteins, hGCP2 and hGCP3, respectively. We isolated a novel gene, alp16(+), as a multicopy su...

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Detalhes bibliográficos
Main Authors: Fujita, Akiko, Vardy, Leah, Garcia, Miguel Angel, Toda, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC117319/
https://ncbi.nlm.nih.gov/pubmed/12134075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.02-01-0603
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