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Effect of internal viral sequences on the utility of retroviral vectors.

Expression of the human ADA cDNA encoded by the Moloney murine leukemia virus spliced RNA form is enhanced by intron-contained sequences. The presence of sequences corresponding to the viral gag gene in a Moloney murine leukemia virus-based vector results in the generation of 10- to 40-fold higher t...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Armentano, D, Yu, S F, Kantoff, P W, von Ruden, T, Anderson, W F, Gilboa, E
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1987
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254147/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3033290/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.5.1647-1650.1987
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