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Adenovirus E1A 12S protein induces DNA synthesis and proliferation in primary epithelial cells in both the presence and absence of serum.

Infection of primary baby rat kidney (BRK) cells with an adenovirus that carries an E1A 12S cDNA in place of the normal E1A region (adenovirus 5 [Ad5] 12S) resulted in the induction of cellular DNA synthesis and proliferation of the epithelial cells in the population, even in the absence of serum. I...

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Pubblicato in:J Virol
Autori principali: Quinlan, M P, Grodzicker, T
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1987
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254006/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3027395/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.3.673-682.1987
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