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Pathogenicity of herpes simplex virus mutants containing drug resistance mutations in the viral DNA polymerase gene.

Three herpes simplex virus mutants that contain drug resistance mutations in the DNA polymerase gene exhibited no significant reduction in replication in the ears of mice compared with the wild type after inoculation at that site but were attenuated for pathogenicity after intracerebral inoculation....

詳細記述

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書誌詳細
出版年:J Virol
主要な著者: Field, H J, Coen, D M
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1986
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253927/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3018291/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.60.1.286-289.1986
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