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Synthesis and Properties of Size-expanded DNAs: Toward Designed, Functional Genetic Systems

We describe the design, synthesis, and properties of DNA-like molecules in which the base pairs are expanded by benzo homologation. The resulting size-expanded genetic helices are called xDNA (“expanded DNA”) and yDNA (“wide DNA”). The large component bases are fluorescent, and they display high sta...

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Detalhes bibliográficos
Main Authors: Krueger, Andrew T., Lu, Haige, Lee, Alex H. F., Kool, Eric T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2539066/
https://ncbi.nlm.nih.gov/pubmed/17309194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ar068200o
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