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Toward a Designed, Functioning Genetic System With Expanded-size Base Pairs: Solution Structure of the 8-Base xDNA Double Helix

We describe the NMR-derived solution structure of the double helical form of a designed 8-base genetic pairing system, termed xDNA. The benzo-homologous xDNA design contains base pairs that are wider than natural DNA pairs by ca. 2.4 Å (the width of a benzene ring). The eight component bases of this...

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Detalhes bibliográficos
Main Authors: Lynch, Stephen R., Liu, Haibo, Gao, Jianmin, Kool, Eric T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519095/
https://ncbi.nlm.nih.gov/pubmed/17090058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja065606n
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