TASK channel deletion in mice causes primary hyperaldosteronism

When inappropriate for salt status, the mineralocorticoid aldosterone induces cardiac and renal injury. Autonomous overproduction of aldosterone from the adrenal zona glomerulosa (ZG) is also the most frequent cause of secondary hypertension. Yet, the etiology of nontumorigenic primary hyperaldoster...

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Detalles Bibliográficos
Main Authors: Davies, Lucinda A., Hu, Changlong, Guagliardo, Nick A., Sen, Neil, Chen, Xiangdong, Talley, Edmund M., Carey, Robert M., Bayliss, Douglas A., Barrett, Paula Q.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538899/
https://ncbi.nlm.nih.gov/pubmed/18250325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712000105
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