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Characterizing the cancer genome in lung adenocarcinoma

Somatic alterations in cellular DNA underlie almost all human cancers1. The prospect of targeted therapies2 and the development of high-resolution, genome-wide approaches3–8 are now spurring systematic efforts to characterize cancer genomes. Here we report a large-scale project to characterize copy-...

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Detalhes bibliográficos
Main Authors: Weir, Barbara A., Woo, Michele S., Getz, Gad, Perner, Sven, Ding, Li, Beroukhim, Rameen, Lin, William M., Province, Michael A., Kraja, Aldi, Johnson, Laura A., Shah, Kinjal, Sato, Mitsuo, Thomas, Roman K., Barletta, Justine A., Borecki, Ingrid B., Broderick, Stephen, Chang, Andrew C., Chiang, Derek Y., Chirieac, Lucian R., Cho, Jeonghee, Fujii, Yoshitaka, Gazdar, Adi F., Giordano, Thomas, Greulich, Heidi, Hanna, Megan, Johnson, Bruce E., Kris, Mark G., Lash, Alex, Lin, Ling, Lindeman, Neal, Mardis, Elaine R., McPherson, John D., Minna, John D., Morgan, Margaret B., Nadel, Mark, Orringer, Mark B., Osborne, John R., Ozenberger, Brad, Ramos, Alex H., Robinson, James, Roth, Jack A., Rusch, Valerie, Sasaki, Hidefumi, Shepherd, Frances, Sougnez, Carrie, Spitz, Margaret R., Tsao, Ming-Sound, Twomey, David, Verhaak, Roel G. W., Weinstock, George M., Wheeler, David A., Winckler, Wendy, Yoshizawa, Akihiko, Yu, Soyoung, Zakowski, Maureen F., Zhang, Qunyuan, Beer, David G., Wistuba, Ignacio I., Watson, Mark A., Garraway, Levi A., Ladanyi, Marc, Travis, William D., Pao, William, Rubin, Mark A., Gabriel, Stacey B., Gibbs, Richard A., Varmus, Harold E., Wilson, Richard K., Lander, Eric S., Meyerson, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538683/
https://ncbi.nlm.nih.gov/pubmed/17982442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06358
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