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Aging, microglial cell priming, and the discordant central inflammatory response to signals from the peripheral immune system

Recent studies suggest that activation of the peripheral immune system elicits a discordant central (i.e., in the brain) inflammatory response in aged but otherwise healthy subjects compared with younger cohorts. A fundamental difference in the reactive state of microglial cells in the aged brain ha...

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Bibliografische gegevens
Hoofdauteurs: Dilger, Ryan N., Johnson, Rodney W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Society for Leukocyte Biology 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538600/
https://ncbi.nlm.nih.gov/pubmed/18495785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0208108
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