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Aging, microglial cell priming, and the discordant central inflammatory response to signals from the peripheral immune system
Recent studies suggest that activation of the peripheral immune system elicits a discordant central (i.e., in the brain) inflammatory response in aged but otherwise healthy subjects compared with younger cohorts. A fundamental difference in the reactive state of microglial cells in the aged brain ha...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Society for Leukocyte Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2538600/ https://ncbi.nlm.nih.gov/pubmed/18495785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0208108 |
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