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Relationship of p220 cleavage during picornavirus infection to 2A proteinase sequencing.

Infection of HeLa cells by poliovirus results in an abrupt inhibition of host cell protein synthesis. It is thought that the mechanism of this inhibition involves proteolytic cleavage of the p220 component of the cap-binding protein complex, thereby causing functional inactivation of the cap-binding...

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Detalhes bibliográficos
Main Authors: Lloyd, R E, Grubman, M J, Ehrenfeld, E
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC253854/
https://ncbi.nlm.nih.gov/pubmed/2845133
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