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Replication and gene expression of hepatitis B virus in a transgenic mouse that contains the complete viral genome.

We have sought to address the problem of the host and tissue specificity of the hepatitis B virus (HBV) by using transgenic mice obtained after injection of head-to-tail dimers of the HBV genome. Viral DNA replication and protein synthesis were obtained in one of nine transgenic mice containing inte...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Farza, H, Hadchouel, M, Scotto, J, Tiollais, P, Babinet, C, Pourcel, C
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253846/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2845128/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.11.4144-4152.1988
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