Effect of Parenteral Antibiotic Administration on Establishment of Intestinal Colonization in Mice by Klebsiella pneumoniae Strains Producing Extended-Spectrum β-Lactamases

A mouse model was used to test the hypothesis that antibiotics with activity against anaerobes promote overgrowth of extended-spectrum β-lactamase-producing Klebsiella pneumoniae strains in stool. Subcutaneous clindamycin consistently promoted establishment of high-density colonization, whereas pipe...

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Autors principals: Hoyen, Claudia K., Pultz, Nicole J., Paterson, David L., Aron, David C., Donskey, Curtis J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC253805/
https://ncbi.nlm.nih.gov/pubmed/14576127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.11.3610-3612.2003
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