Ring Expanded Nucleoside Analogues Inhibit RNA Helicase and Intracellular Human Immunodeficiency virus type 1 Replication

A series of ring expanded nucleoside (REN) analogues were synthesized and screened for inhibition of cellular RNA helicase activity and human immunodeficiency virus type 1 (HIV-1) replication. We identified two compounds 1 and 2 that inhibited the ATP dependent activity of human RNA helicase DDX3. C...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Yedavalli, Venkat S.R.K, Zhang, Ning, Cai, Hongyi, Zhang, Peng, Starost, Matthew F., Hosmane, Ramachandra S., Jeang, Kuan-Teh
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2537995/
https://ncbi.nlm.nih.gov/pubmed/18680273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm800332m
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge