A molecularly cloned hepatitis B virus produced in vitro is infectious in a chimpanzee.

The infectivity of hepatitis B virus (HBV) produced in vitro by HepG2 cells transfected with HBV DNA (HepG2T14) has been assayed in a chimpanzee. Following inoculation, the chimpanzee underwent a typical course of type B hepatitis infection, characterized by elevation of serum aminotransferases and...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Sureau, C, Eichberg, J W, Hubbard, G B, Romet-Lemonne, J L, Essex, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253751/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3392775/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.8.3064-3067.1988
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