A molecularly cloned hepatitis B virus produced in vitro is infectious in a chimpanzee.

The infectivity of hepatitis B virus (HBV) produced in vitro by HepG2 cells transfected with HBV DNA (HepG2T14) has been assayed in a chimpanzee. Following inoculation, the chimpanzee underwent a typical course of type B hepatitis infection, characterized by elevation of serum aminotransferases and...

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Bibliographische Detailangaben
Hauptverfasser: Sureau, C, Eichberg, J W, Hubbard, G B, Romet-Lemonne, J L, Essex, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1988
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC253751/
https://ncbi.nlm.nih.gov/pubmed/3392775
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