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A Constitutively “Phosphorylated” Guanylyl Cyclase-linked Atrial Natriuretic Peptide Receptor Mutant Is Resistant to Desensitization

Dephosphorylation of the natriuretic peptide receptor-A (NPR-A) is hypothesized to mediate its desensitization in response to atrial natriuretic peptide (ANP) binding. Recently, we identified six phosphorylation sites within the kinase homology domain of NPR-A and determined that the conversion of t...

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Autori principali: Potter, Lincoln R., Hunter, Tony
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC25375/
https://ncbi.nlm.nih.gov/pubmed/10359598
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