Purification of the herpes simplex virus type 1 65-kilodalton DNA-binding protein: properties of the protein and evidence of its association with the virus-encoded DNA polymerase.

Using a combination of conventional column chromatography and velocity sedimentation, we have purified the 65-kilodalton DNA-binding protein (65KDBP) encoded by herpes simplex virus (HSV) greater than 625-fold. The HSV type 1 (HSV-1)-encoded DNA polymerase (pol) cofractionated with 65KDBP through DE...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Gallo, M L, Jackwood, D H, Murphy, M, Marsden, H S, Parris, D S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253724/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2839706/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.8.2874-2883.1988
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