Purification of the herpes simplex virus type 1 65-kilodalton DNA-binding protein: properties of the protein and evidence of its association with the virus-encoded DNA polymerase.

Using a combination of conventional column chromatography and velocity sedimentation, we have purified the 65-kilodalton DNA-binding protein (65KDBP) encoded by herpes simplex virus (HSV) greater than 625-fold. The HSV type 1 (HSV-1)-encoded DNA polymerase (pol) cofractionated with 65KDBP through DE...

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Detalhes bibliográficos
Main Authors: Gallo, M L, Jackwood, D H, Murphy, M, Marsden, H S, Parris, D S
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC253724/
https://ncbi.nlm.nih.gov/pubmed/2839706
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