High oxygen prevents fetal lethality due to lack of catecholamines

The catecholamine norepinephrine is required for fetal survival, but its essential function is unknown. When catecholamine-deficient [tyrosine hydroxylase (Th) null] mouse fetuses die at embryonic day (E)13.5–14.5, they resemble wild-type (wt) fetuses exposed to hypoxia. They exhibit bradycardia (28...

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Bibliografiske detaljer
Main Authors: Ream, Margie A., Chandra, Rashmi, Peavey, Mary, Ray, Alisa M., Roffler-Tarlov, Suzanne, Kim, Hyung-Gun, Wetsel, William C., Rockman, Howard A., Chikaraishi, Dona M.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2008
Fag:
Exercise and Respiratory Physiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536863/
https://ncbi.nlm.nih.gov/pubmed/18635452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00860.2007
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