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Overexpression of progesterone receptor B increases sensitivity of human colon muscle cells to progesterone

Colon muscle strips and cells from female patients with slow-transit constipation (STC) exhibit impaired motility, signal transduction abnormalities characterized by downregulation of G(q/11) and upregulation of G(s) proteins, decreased cyclooxygenase (COX)-1 and thromboxane (Tx)B(2) levels, increas...

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Detalles Bibliográficos
Main Authors: Cheng, Ling, Pricolo, Victor, Biancani, Piero, Behar, Jose
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536785/
https://ncbi.nlm.nih.gov/pubmed/18776045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90214.2008
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