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Bias-reduced estimators and confidence intervals for odds ratios in genome-wide association studies

Genome-wide association studies (GWAS) provide an important approach to identifying common genetic variants that predispose to human disease. A typical GWAS may genotype hundreds of thousands of single nucleotide polymorphisms (SNPs) located throughout the human genome in a set of cases and controls...

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Detalhes bibliográficos
Main Authors: Zhong, Hua, Prentice, Ross L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536726/
https://ncbi.nlm.nih.gov/pubmed/18310059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxn001
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