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Amyloid beta toxicity dependent upon endothelial cell state
Amyloid beta (Aβ), a peptide family produced and deposited in neurons and endothelial cells (EC), is found at subnanomolar concentrations in the plasma of healthy individuals. Simple conformational changes produce a form of Aβ Aβ42, which creates toxic plaque in the brains of Alzheimer’s patients. O...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2536632/ https://ncbi.nlm.nih.gov/pubmed/18601976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2008.06.061 |
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