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Amyloid beta toxicity dependent upon endothelial cell state

Amyloid beta (Aβ), a peptide family produced and deposited in neurons and endothelial cells (EC), is found at subnanomolar concentrations in the plasma of healthy individuals. Simple conformational changes produce a form of Aβ Aβ42, which creates toxic plaque in the brains of Alzheimer’s patients. O...

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Detalhes bibliográficos
Main Authors: Balcells, Mercedes, Wallins, Joseph S., Edelman, Elazer R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536632/
https://ncbi.nlm.nih.gov/pubmed/18601976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2008.06.061
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