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Insertional mutagenesis of the Abelson murine leukemia virus genome: identification of mutants with altered kinase activity and defective transformation ability.

A library of Abelson murine leukemia virus (A-MuLV) proviral DNAs with 12- or 6-base-pair (bp) insertional mutations was constructed. The 29 mutations characterized spanned the entire protein-coding region of the provirus. We tested the effects of these mutations both on the kinase activity of the g...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Rees-Jones, R W, Goff, S P
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1988
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253657/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2828693/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.3.978-986.1988
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