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Insertional mutagenesis of the Abelson murine leukemia virus genome: identification of mutants with altered kinase activity and defective transformation ability.

A library of Abelson murine leukemia virus (A-MuLV) proviral DNAs with 12- or 6-base-pair (bp) insertional mutations was constructed. The 29 mutations characterized spanned the entire protein-coding region of the provirus. We tested the effects of these mutations both on the kinase activity of the g...

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Bibliografiska uppgifter
Huvudupphovsmän: Rees-Jones, R W, Goff, S P
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1988
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC253657/
https://ncbi.nlm.nih.gov/pubmed/2828693
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