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Stabilization of β-catenin in XY gonads causes male-to-female sex-reversal
During mammalian sex determination, expression of the Y-linked gene Sry shifts the bipotential gonad toward a testicular fate by upregulating a feed-forward loop between FGF9 and SOX9 to establish SOX9 expression in somatic cells. We previously proposed that these signals are mutually antagonistic w...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2536503/ https://ncbi.nlm.nih.gov/pubmed/18617533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn193 |
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