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PAI-1 stimulates fibronectin matrix assembly in osteosarcoma cells through crosstalk between the αvβ5 and α5β1 integrins

The plasminogen activation system regulates matrix remodeling through both proteolytic and non-proteolytic mechanisms. Studies were undertaken to determine the effects of the plasminogen activator inhibitor 1 (PAI-1) on fibronectin matrix assembly. The addition of PAI-1 to MG-63 cells caused a 1.5–3...

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Hlavní autoři: Vial, Daniel, McKeown-Longo, Paula J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2535923/
https://ncbi.nlm.nih.gov/pubmed/18445685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.020149
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