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Genetic Basis of Evolutionary Adaptation by Escherichia coli to Stressful Cycles of Freezing, Thawing and Growth

Microbial evolution experiments offer a powerful approach for coupling changes in complex phenotypes, including fitness and its components, with specific mutations. Here we investigate mutations substituted in 15 lines of Escherichia coli that evolved for 1000 generations under freeze–thaw–growth (F...

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Autors principals: Sleight, Sean C., Orlic, Christian, Schneider, Dominique, Lenski, Richard E.
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2535694/
https://ncbi.nlm.nih.gov/pubmed/18757947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.091330
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