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Insulinlike growth factor II expression and oval cell proliferation associated with hepatocarcinogenesis in woodchuck hepatitis virus carriers.

Insulinlike growth factor II (IGF-II) is a highly mitogenic fetal growth factor suspected of regulating the growth of a wide spectrum of tissues via an autocrine or paracrine mode of action or both. High steady-state levels of IGF-II RNA were detected in 45% of hepatocellular carcinomas (HCCs) arisi...

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Autors principals: Fu, X X, Su, C Y, Lee, Y, Hintz, R, Biempica, L, Snyder, R, Rogler, C E
Format: Artigo
Idioma:Inglês
Publicat: 1988
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC253466/
https://ncbi.nlm.nih.gov/pubmed/2457114
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