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Chemical Transformation of Prostaglandin-A(2): A Novel Series of C-10 Halogenated, C-12 Hydroxylated Prostaglandin-A(2) Analogues

[Image: see text] Synthesis of a novel class of C-10 halogenated and C-12 oxygenated prostaglandin-A(2) derivatives 6(a–c) has been accomplished. (15S)-Prostaglandin-A(2) (1), from the gorgonian Plexaura homomalla, served as the starting material for the synthesis. The absolute configuration was det...

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Detalhes bibliográficos
Main Authors: Ratnayake, Anokha S., Bugni, Tim S., Veltri, Charles A., Skalicky, Jack J., Ireland, Chris M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533845/
https://ncbi.nlm.nih.gov/pubmed/16671809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol0606583
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