Molecular Shape, Architecture, and Size of P2X(4) Receptors Determined Using Fluorescence Resonance Energy Transfer and Electron Microscopy

P2X receptors are ATP-gated nonselective cation channels with important physiological roles. However, their structures are poorly understood. Here, we analyzed the architecture of P2X receptors using fluorescence resonance energy transfer (FRET) microscopy and direct structure determination using el...

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Detalhes bibliográficos
Main Authors: Young, Mark T., Fisher, James A., Fountain, Samuel J., Ford, Robert C., North, R. Alan, Khakh, Baljit S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Membrane Transport, Structure, Function, and Biogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533801/
https://ncbi.nlm.nih.gov/pubmed/18635539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804458200
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