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The transcription factor snail represses Crumbs3 expression and disrupts apico-basal polarity complexes

In epithelial cells, the tight junction divides the plasma membrane into distinct apical and basolateral domains. Polarization is essential for epithelial cell function, and apico-basal cell polarity is lost during the epithelial to mesenchymal transition (EMT), a program of events characterized not...

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Hlavní autoři: Whiteman, EL, Liu, C-J, Fearon, ER, Margolis, B
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533733/
https://ncbi.nlm.nih.gov/pubmed/18246119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.9
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