Antifungal Resistance of Candida glabrata Vaginal Isolates and Development of a Quantitative Reverse Transcription-PCR-Based Azole Susceptibility Assay

A multiplex quantitative reverse transcription-PCR assay was developed to detect azole resistance in Candida glabrata, an important opportunistic pathogen that develops resistance rapidly. Resistance was defined as a ≥3-fold increase in CDR1 expression by this assay, which proved to be 100% sensitiv...

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Detalhes bibliográficos
Main Authors: Gygax, Scott E., Vermitsky, John-Paul, Chadwick, Sean G., Self, Matthew J., Zimmerman, Jessica A., Mordechai, Eli, Adelson, Martin E., Trama, Jason P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533493/
https://ncbi.nlm.nih.gov/pubmed/18591262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00462-08
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