Emergence and Acquisition of Fluoroquinolone-Resistant Gram-Negative Bacilli in the Intestinal Tracts of Mice Treated with Fluoroquinolone Antimicrobial Agents

After mice received orogastric administration of a fluoroquinolone-resistant Klebsiella pneumoniae strain, subcutaneous treatment with ciprofloxacin, levofloxacin, and moxifloxacin promoted persistent low-density colonization in 10% to 40% of the mice, whereas treatment with clindamycin consistently...

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Main Authors: Pultz, Michael J., Nerandzic, Michelle M., Stiefel, Usha, Donskey, Curtis J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Experimental Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533488/
https://ncbi.nlm.nih.gov/pubmed/18606843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00117-08
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