In Vitro and In Vivo Studies of the Trypanocidal Activity of a Diarylthiophene Diamidine against Trypanosoma cruzi

Aromatic diamidines are DNA minor groove-binding ligands that display excellent antimicrobial activity against fungi, bacteria, and protozoa. Due to the currently unsatisfactory chemotherapy for Chagas’ disease and in view of our previous reports regarding the effect of diamidines and analogues agai...

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Detalhes bibliográficos
Main Authors: da Silva, Cristiane França, Batista, Marcos Meuser, Batista, Denise da Gama Jaen, de Souza, Elen Mello, da Silva, Patrícia Bernardino, de Oliveira, Gabriel Melo, Meuser, Andrea Souza, Shareef, Abdur-Rafay, Boykin, David W., Soeiro, Maria de Nazaré C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533474/
https://ncbi.nlm.nih.gov/pubmed/18625779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00038-08
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