Evaluation of Daptomycin Pharmacodynamics and Resistance at Various Dosage Regimens against Staphylococcus aureus Isolates with Reduced Susceptibilities to Daptomycin in an In Vitro Pharmacodynamic Model with Simulated Endocardial Vegetations

The need to investigate novel dosing regimens and combinations is essential in combating poor treatment outcomes for Staphylococcus aureus bacteremia and endocarditis. We evaluated the impact of simulated standard- and high-dose daptomycin in combination with gentamicin or rifampin against daptomyci...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Rose, Warren E., Leonard, Steven N., Rybak, Michael J.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2008
נושאים:
Pharmacology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533470/
https://ncbi.nlm.nih.gov/pubmed/18591272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00102-08
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