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In Vitro and In Vivo Treatments of Echinococcus Protoscoleces and Metacestodes with Artemisinin and Artemisinin Derivatives

In vitro treatment of Echinococcus multilocularis and Echinococcus granulosus larval stages with the antimalarials dihydroartemisinin and artesunate (10 to 40 μM) exhibited promising results, while 6 weeks of in vivo treatment of mice infected with E. multilocularis metacestodes (200 mg/kg of body w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Spicher, Martin, Roethlisberger, Carole, Lany, Catharina, Stadelmann, Britta, Keiser, Jennifer, Ortega-Mora, Luis M., Gottstein, Bruno, Hemphill, Andrew
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533465/
https://ncbi.nlm.nih.gov/pubmed/18625777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00553-08
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