In Vitro and In Vivo Treatments of Echinococcus Protoscoleces and Metacestodes with Artemisinin and Artemisinin Derivatives

In vitro treatment of Echinococcus multilocularis and Echinococcus granulosus larval stages with the antimalarials dihydroartemisinin and artesunate (10 to 40 μM) exhibited promising results, while 6 weeks of in vivo treatment of mice infected with E. multilocularis metacestodes (200 mg/kg of body w...

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Detalhes bibliográficos
Main Authors: Spicher, Martin, Roethlisberger, Carole, Lany, Catharina, Stadelmann, Britta, Keiser, Jennifer, Ortega-Mora, Luis M., Gottstein, Bruno, Hemphill, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533465/
https://ncbi.nlm.nih.gov/pubmed/18625777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00553-08
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