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Mutations in the fks1 Gene in Candida albicans, C. tropicalis, and C. krusei Correlate with Elevated Caspofungin MICs Uncovered in AM3 Medium Using the Method of the European Committee on Antibiotic Susceptibility Testing

Mutations in two specific regions of the Fks1 subunit of 1,3-β-d-glucan synthase are known to confer decreased caspofungin susceptibility on Candida spp. Clinical isolates of Candida spp. (404 Candida albicans, 62 C. tropicalis, and 21 C. krusei isolates) sent to the French National Reference Center...

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Bibliografski detalji
Glavni autori: Desnos-Ollivier, Marie, Bretagne, Stéphane, Raoux, Dorothée, Hoinard, Damien, Dromer, Françoise, Dannaoui, Eric
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533459/
https://ncbi.nlm.nih.gov/pubmed/18591282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00088-08
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