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Stability of Colistin Methanesulfonate in Pharmaceutical Products and Solutions for Administration to Patients
Colistin methanesulfonate (CMS) has the potential to hydrolyze in aqueous solution to liberate colistin, its microbiologically active and more toxic parent compound. While conversion of CMS to colistin in vivo is important for bactericidal activity, liberation of colistin during storage and/or use o...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2533443/ https://ncbi.nlm.nih.gov/pubmed/18606838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00103-08 |
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