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Genetic complementation among poliovirus mutants derived from an infectious cDNA clone.

We constructed several well-defined mutations in the nonstructural portion of the poliovirus type I (Mahoney strain) genome by making small insertions in an infectious cDNA clone. The derived viral strains carrying the mutations exhibited a variety of distinct plaque phenotypes. Thus, we were able t...

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Bibliographic Details
Published in:J Virol
Main Authors: Bernstein, H D, Sarnow, P, Baltimore, D
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1986
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253343/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3023656/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.60.3.1040-1049.1986
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