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Genetic complementation among poliovirus mutants derived from an infectious cDNA clone.

We constructed several well-defined mutations in the nonstructural portion of the poliovirus type I (Mahoney strain) genome by making small insertions in an infectious cDNA clone. The derived viral strains carrying the mutations exhibited a variety of distinct plaque phenotypes. Thus, we were able t...

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Detalles Bibliográficos
Main Authors: Bernstein, H D, Sarnow, P, Baltimore, D
Formato: Artigo
Idioma:Inglês
Publicado: 1986
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC253343/
https://ncbi.nlm.nih.gov/pubmed/3023656
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