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Simian virus 40 (SV40) T antigen binds specifically to double-stranded DNA but not to single-stranded DNA or DNA/RNA hybrids containing the SV40 regulatory sequences.

Simian virus 40 T antigen has been shown previously to bind specifically with high affinity to sites within the regulatory region of double-stranded simian virus 40 DNA. Using competition filter binding and the DNA-binding immunoassay, we show that T antigen did not bind specifically to either early...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Auborn, K J, Markowitz, R B, Wang, E, Yu, Y T, Prives, C
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1988
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253332/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3367427/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.6.2204-2208.1988
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