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Regeneration of herpesviruses from molecularly cloned subgenomic fragments.

The ability to manipulate the genomes of herpesviruses is of eminent importance for obtaining insight into gene function and regulation of gene expression of these complex viruses. Here we report the use of in vivo overlap recombination to generate pseudorabies virus mutants. Cotransfection of up to...

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Autores principales: van Zijl, M, Quint, W, Briaire, J, de Rover, T, Gielkens, A, Berns, A
Formato: Artigo
Lenguaje:Inglês
Publicado: 1988
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC253328/
https://ncbi.nlm.nih.gov/pubmed/2835520
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