Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome

Bile salt hydrolases (BSHs) catalyze the “gateway” reaction in a wider pathway of bile acid modification by the gut microbiota. Because bile acids function as signaling molecules regulating their own biosynthesis, lipid absorption, cholesterol homeostasis, and local mucosal defenses in the intestine...

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Bibliographic Details
Main Authors: Jones, Brian V., Begley, Máire, Hill, Colin, Gahan, Cormac G. M., Marchesi, Julian R.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2008
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533232/
https://ncbi.nlm.nih.gov/pubmed/18757757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804437105
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