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Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome

Bile salt hydrolases (BSHs) catalyze the “gateway” reaction in a wider pathway of bile acid modification by the gut microbiota. Because bile acids function as signaling molecules regulating their own biosynthesis, lipid absorption, cholesterol homeostasis, and local mucosal defenses in the intestine...

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Hlavní autoři: Jones, Brian V., Begley, Máire, Hill, Colin, Gahan, Cormac G. M., Marchesi, Julian R.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533232/
https://ncbi.nlm.nih.gov/pubmed/18757757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804437105
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