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Synthetic glycopeptide vaccines combining β-mannan and peptide epitopes induce protection against candidiasis

The first fully synthetic glycopeptide vaccines against a fungal disease have been used to combat disseminated candidiasis in mice. Six T cell peptides found in Candida albicans cell wall proteins were selected by algorithm peptide epitope searches; each was synthesized and conjugated to the fungal...

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Bibliografische gegevens
Hoofdauteurs: Xin, Hong, Dziadek, Sebastian, Bundle, David R., Cutler, Jim E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533223/
https://ncbi.nlm.nih.gov/pubmed/18725625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803195105
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