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Synthetic glycopeptide vaccines combining β-mannan and peptide epitopes induce protection against candidiasis
The first fully synthetic glycopeptide vaccines against a fungal disease have been used to combat disseminated candidiasis in mice. Six T cell peptides found in Candida albicans cell wall proteins were selected by algorithm peptide epitope searches; each was synthesized and conjugated to the fungal...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2533223/ https://ncbi.nlm.nih.gov/pubmed/18725625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803195105 |
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